BELGRADE, Mont., Aug. 12, 2014 (GLOBE NEWSWIRE) -- Bacterin International Holdings, Inc. (NYSE MKT:BONE), a leader in the development of bone graft materials and bioactive coatings for medical applications, announced today The Spine Journal has published positive results reported on the evaluation of OsteoSelect® DBM Putty in a rabbit posterolateral spinal fusion model. The study was completed by the Integrated Spine Research Department at the Hospital for Special Surgery in New York.

The study compared the efficacy of autologous bone, frequently referred to as the gold standard for achieving fusion, and Bacterin's OsteoSelect® DBM Putty in a commonly utilized animal model used to assess spinal fusion. The results showed equivalence between the two groups, based on biomechanical, radiographic and histological analyses, with the OsteoSelect® group producing more mature fusion masses relative to autograft. These results may support a surgeon's selection of OsteoSelect® DBM Putty as an effective grafting material during spinal arthrodesis procedures, of which there are over 325,000 annually in the United States.

"Bacterin is pleased to announce the publication of another peer-reviewed study supporting the efficacy of our demineralized bone matrix technologies," said Gregory Juda, Chief Scientific Officer for Bacterin. "We are excited that OsteoSelect® has shown equivalency in this preclinical model to autograft, the gold standard in bone grafting materials. We expect subsequent clinical research to further validate these findings."

OsteoSelect® DBM Putty is a malleable bone grafting material comprised of demineralized bone matrix allograft combined with a polymer carrier material. The product was engineered using feedback from key opinion leaders in several orthopedic specialties, with a focus on providing solutions to the shortcomings inherent to other commercially available DBM products. The bone forming potential of every lot of OsteoSelect® is confirmed after sterilization in an animal model thus providing surgeons with a bone grafting solution that is both safe and confirmed to be biologically active.

The full article may be accessed on The Spine Journal, titled Evaluation of a new formulation of demineralized bone matrix putty in a rabbit posterolateral spinal fusion model.

About Bacterin International Holdings

Bacterin International Holdings, Inc. (NYSE MKT:BONE) develops, manufactures and markets biologics products to domestic and international markets. These products are used in a variety of applications including enhancing fusion in spine surgery, relief of back pain, promotion of bone growth in foot and ankle surgery, promotion of cranial healing following neurosurgery and subchondral repair in knee and other joint surgeries.

Bacterin's Medical Device division develops, employs, and licenses coatings for various medical device applications. For further information, please visit www.bacterin.com.

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